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Absence of a critical period in estrogen-induced release of LH in the anestrous ewe

, : Absence of a critical period in estrogen-induced release of LH in the anestrous ewe. Endocrinology 94(3): 918-920

Anoestrous ewes were given a single injection of oil at 06.30 h or of 50 mu g oestradiol benzoate (OB) at 06.00, 12.00, or 18.00 h. Blood samples were collected at the time of injection and at 3-h intervals for 27 h. Serum LH levels were significantly elevated within 6-12 h after the injection of OB. Peak levels of LH occurred at 19.20, 00.35 or 06.00 h, all approx. 12 h following injection of OB.


PMID: 4855946

DOI: 10.1210/endo-94-3-918

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