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Absorption of iron from sustained release and rapidly disintegrating tablets. Influence of daily numbers of administrations

, : Absorption of iron from sustained release and rapidly disintegrating tablets. Influence of daily numbers of administrations. Acta Medica Scandinavica 194(1/2): 123-127

In absorption studies with 59Fe-labelled tablets, 20 male blood donors and 14 patients with iron-deficiency anaemia were given 100 mg ferrous Fe twice daily from a sustained-release preparation or 50 mg Fe 4 times daily from rapidly disintegrating ferrous sulphate. The blood donors absorbed the same amount of Fe from both preparations, whereas the patients with anaemia absorbed significantly more Fe from the sustained-release preparation. The time of intake of the second daily dose of sustained-release preparation had no significant effect on absorption.


PMID: 4727245

DOI: 10.1111/j.0954-6820.1973.tb19416.x

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