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Absorption, excretion, and metabolism of Robenz, robenidine hydrochloride , in the rat

, : Absorption, excretion, and metabolism of Robenz, robenidine hydrochloride , in the rat. Journal of Agricultural and Food Chemistry 21(5): 794-797

Rats given by mouth labelled robenidine hydrochloride, the active ingredient in Robenz, a premix coccidiostat, excreted about 58% of 14C in faeces and 20% in urine within 24 h. p-Chlorohippuric and p-chlorobenzoic acids accounted for 88 and 2%, respectively, of total 14C in urine. Faeces contained most 14C as unmetabolised robenidine. Tissue retention was only 0.4% of the dose after 96 h.


DOI: 10.1021/jf60189a011

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