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Acceleration of dextransucrase activity of Streptococcus mutans by secretory immunoglobulin A

, : Acceleration of dextransucrase activity of Streptococcus mutans by secretory immunoglobulin A. Journal of Bacteriology 118(3): 805-809

Dextran synthesis by Str. mutans was increased approx. 3-fold in the presence of human salivary IgA and >7-fold in the presence of human colostral IgA; these increases even occurred with chemically-denatured salivary IgA and heat-denatured (100 deg C for 10 min) colostral IgA. Serum IgA and IgG did not affect dextran synthesis, whilst rabbit antiserum specific for dextransucrase completely inhibited synthesis.


PMID: 4208412

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