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Control of rat adipose tissue metabolism by cortisone in relation to epinephrine

, : Control of rat adipose tissue metabolism by cortisone in relation to epinephrine. American Journal of Physiology 224(4): 898-903

Epididymal fat pads from normal rats and those with bilateral adrenalectomy or partial adrenal medullectomy were treated in vivo with graded doses of adrenaline. The highest lipolytic response was obtained with a dose of 100 mu g/100 g rat, injected only 5 min before the rats were killed. The greatest effect with cortisone was obtained with a dose of 50 mu g/100 g given 30 min before. The effect of either hormone given alone was much less than in combination.


PMID: 4698807

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