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Derivation of an isolate of low virulence from the Essex '70 strain of Newcastle disease virus

, : Derivation of an isolate of low virulence from the Essex '70 strain of Newcastle disease virus. Veterinary Record 94(2): 38-41

ND virus of low virulence was derived from the virulent 'Essex '70' strain by passage to limiting dilutions in chick embryos and the selection of the last egg to die or infected embryos still alive six or seven days after infection. The intracerebral pathogenicity index of the virus was shown to diminish with passage from an initial 1.65 to 0.44 by the 15th passage.


PMID: 4818678

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