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Effect of estradiol on pregnant mare's serum (PMS)-induced ovulation in the immature rat

, : Effect of estradiol on pregnant mare's serum (PMS)-induced ovulation in the immature rat. Fertility and Sterility 23(10): 769-775

Oestradiol administered at the same time as PMS appeared to inhibit PMS-induced ovulation in 24-day-old rats killed 72 h after treatment. However, autopsy at 48 h showed that a premature ovulation had occurred. Premature ovulation did not occur when the oestrogen was injected 24-52 h after PMS. A dose of 2.5-80 mu g oestradiol induced premature ovulation, but one of <2.5 mu g had no effect. Oestradiol interacted with progesterone in the induction of premature ovulation.


PMID: 4651629

Other references

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