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Effect of extreme calcium deprivation on degree of mineralization of alveolar bone, dentin and enamel in rats


, : Effect of extreme calcium deprivation on degree of mineralization of alveolar bone, dentin and enamel in rats. Scandinavian Journal of Dental Research 80(4): 327-333

Of 12 female rats 4.5 months old 6 were given to appetite a diet with 0.08% Ca and less than 1 mg F/kg. Ammonium oxalate was added to the diet in amount calculated to precipitate 12.5 mg Ca/day provided the daily intake was 10 g/rat. Intraperitoneal injections of 40 mg EDTA, which will chelate 4 mg Ca, were given 5 times a week for 5 weeks. Controls were given the same diet but with 1.1% Ca added and without oxalate. The rats were given the diet for 35 days and were then killed.

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PMID: 4627005


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