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Studies on the pathogenesis of tetanus with 125I-labelled toxin


, : Studies on the pathogenesis of tetanus with 125I-labelled toxin. Radioactive tracers in microbial immunology: 67-76

In labelling tetanus toxin with radioisotopes of iodine, the lowest amount of Chloramine-T should be used because of the high sensitivity of the protein towards oxidizing agents. Upon i/v injection of labelled toxin in rats, the radioactivity of liver and muscle decreased concomitantly with that of plasma. Cerebrum and cerebellum take up only traces of radioactivity.

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