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Studies on the regulation of glutathione level in rat liver


, : Studies on the regulation of glutathione level in rat liver. Journal of Biochemistry 75(1): 93-103

The glutathione (GSH) and glucose-6-phosphate dehydrogenase contents of liver decreased when rats were starved for 1 or 2 days and returned to normal after refeeding; the reduction in ATP/ADP ratio produced by starving eventually increased after refeeding. Turnover and degradation of GSH was more rapid in starved than in refed rats. As the increase in GSH after refeeding was not prevented by actinomycin D or cycloheximide it apparently did not involve new protein synthesis.

US$29.90

PMID: 4151174


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