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Studies on the relation between zinc and malignant tumor. 2. Effects of zinc on hepatoma of rats treated with DEN


, : Studies on the relation between zinc and malignant tumor. 2. Effects of zinc on hepatoma of rats treated with DEN. Journal of Nara Medical Association 23(3): 177-186

2. Rats were given in their drinking water Zn 50, 500 or 1000 mg/litre without or with 0.005% N-nitrosodiethylamine (DEN) to produced hepatoma. One group was given DEN alone and controls had no DEN or Zn. The weight of rats given 50 mg Zn/litre rose significantly. When 1000 mg Zn/litre was given Zn in testes and liver rose significantly. There was no significant difference between Zn contents in normal liver and that with a tumour.

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