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Studies on the role of histamine and 5-hydroxytryptamine in immunity against the nematode Trichostrongylus colubriformis. III. Inhibition of worm expulsion from guinea pigs by treatment with reserpine


, : Studies on the role of histamine and 5-hydroxytryptamine in immunity against the nematode Trichostrongylus colubriformis. III. Inhibition of worm expulsion from guinea pigs by treatment with reserpine. International Archives of Allergy and Applied Immunology 47(6): 875-886

Reserpine treatment inhibited the expulsion of T. colubriformis by adoptively immunized guinea-pigs, but similar treatment of immune cell donors did not inhibit the capacity of their mesenteric lymph node cells to transfer immunity against the parasite. The treatment schedule used in the experiments decreased the levels of both histamine and 5-hydroxytryptamine in the small intestinal mucosa.

US$29.90

PMID: 4154312


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