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The in vitro response of chicken B cell populations to lipopolysaccharide


, : The in vitro response of chicken B cell populations to lipopolysaccharide. Journal of Immunology 111(4): 1277-1280

Chromosomally marked embryonic bursal cells were transferred to B cell depleted chicks and allowed to differentiate in vivo for several weeks. Subsequent evaluation of host and donor cell proliferation in lipopolysaccharide (LPS)-stimulated spleen and peripheral blood lymphocyte cultures of cell recipients established that bursa-derived donor cells (B2 cells) in spleen and blood were capable of responding to LPS. The results furthermore suggested a weak response of host T cells to LPS.

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PMID: 4580670


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