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Failure of stalk-median eminence (SME) extract to suppress serum prolactin levels in rats with hypothalamic islands

, : Failure of stalk-median eminence (SME) extract to suppress serum prolactin levels in rats with hypothalamic islands. Brain Research 125(1): 170-174

Male Sprague-Dawley rats prepared with hypothalamic islands and intact controls both received SME extract or saline vehicle infused intravenously. Blood samples collected 40 min after SME infusion were assayed for prolactin and corticosterone. Infusion of SME but not saline into intact controls produced the expected decrease (P < 0.02) in serum prolactin. In contrast neither saline nor SME infusion suppressed serum prolactin in the animals with hypothalamic islands.


PMID: 851872

DOI: 10.1016/0006-8993(77)90370-5

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