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Origins of antibody diversity: insights gained from amino acid sequence studies of elicited antibodies


, : Origins of antibody diversity: insights gained from amino acid sequence studies of elicited antibodies. Cold Spring Harbor Symposia on Quantitative Biology 41(2): 647-659

This is a review, mainly of work on the rabbit but including experiments on mice, in which the evidence for and against the germ-line and somatic mutation theories for the control of immunoglobulin V-region diversity is considered.

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