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Results of protection trials against schistosomal re-infection (S. haematobium and S. mansoni) in endemic areas after treatment with inactivated cercariae


, : Results of protection trials against schistosomal re-infection (S. haematobium and S. mansoni) in endemic areas after treatment with inactivated cercariae. Sante et developpement 1er Congr Internat Sci Med Madagascar, Tananarive, 2-12 Apr 1968 Crtrav Vol 1: 213-221

In patients infected with Schistosoma mansoni or S. haematobium treated with niridazole at 25 mg/kg body-weight for 7 days there appeared precipitating antibodies, apparently protective. This protection lasted for 90 to 100 days after treatment and this period was extended by intradermal injection of inactivated cercariae. In children infected with S. haematobium and treated and vaccinated the protection lasted for 16 to 21 months.

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