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Retardation of guinea pig sperm acrosome reaction by glucose: the possible importance of pyruvate and lactate metabolism in capacitation and the acrosome reaction

, : Retardation of guinea pig sperm acrosome reaction by glucose: the possible importance of pyruvate and lactate metabolism in capacitation and the acrosome reaction. Biology of Reproduction 13(5): 568-575

The occurrence of the acrosome reaction was used as an index of the completion of capacitation in vitro of guinea-pig spermatozoa. Glucose was found to retard the initiation of the acrosome reaction in media that allow capacitation of guinea-pig spermatozoa. Media containing only pyruvate or pyruvate plus lactate as energy sources induced the earliest acrosome reaction.


PMID: 1203412

DOI: 10.1095/biolreprod13.5.568

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