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Reversal of ineffective erythropoiesis in pernicious anaemia following vitamin B12 therapy


, : Reversal of ineffective erythropoiesis in pernicious anaemia following vitamin B12 therapy. British Journal of Haematology 35(2): 217-224

Ineffective erythropoiesis was quantitated in a series of patients with pernicious anaemia at different times in relation to vitamin B12 therapy by measuring the incorporation of [15N]delta aminolaevulinic acid and [15N]glycine into early labelled bilirubin. Prior to therapy ineffective erythropoiesis was grossly increased but this was reversed within 24 h of giving vitamin B12, suggesting that most of the existing megaloblasts are enabled to mature into circulating red cells.

US$19.90

PMID: 857850

DOI: 10.1111/j.1365-2141.1977.tb00578.x


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Ciganovic, P.; Milosevic, Z.; Kljajic, R.; Herceg, Z.; Horsic, E., 1990: Study on the tolerance of thiophosphate radiation protection agents by pigs. Twelve 5-month-old pigs of 40 kg body weight were given ethiofos or cistafos at 100, 150 or 200 mg/kg body weight i.m. Mild symptoms of toxicity appeared with the 100 mg/kg dosage; these increased in severity with increasing dosage. The maximum to...

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Lenz, J., 1985: Mechanics of the relation between dental prosthetics and materials technology: current problems, results and possibilities for solutions (I). Die Quintessenz 36(4): 755-761

Howell R.R., 1984: Echo abnormalities in mucopolysaccharidoses. Pediatric Cardiology: 262

Uma, G., 1993: Sustainable livelihood security of villages surrounding the Pichavaram mangrove forest, India. Mangrove ecosystems are now receiving a great deal of international scholarly attention. This paper focuses on the Pichavaram mangrove forest of Tamil Nadu state, India. Fifteen hamlets/villages in and around the forest were surveyed during the pe...

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Schopf, T.J.M., 1982: A critical assessment of punctuated equilibria 1 Duration of taxa. Evolution 36.6: 1144-1157

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Nolte, A., 1949: Untersuchungen uber die Rheotaxis dor Anuren-larven. Biologisches Zentralblatt Leipzig, 687-8: 312-321