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Reversible changes of the muscle cell in experimental phosphorus deficiency


, : Reversible changes of the muscle cell in experimental phosphorus deficiency. Journal of Clinical Investigation 57(4): 1019-1024

Eight dogs were given a diet deficient in P for 28 days and then with P supplements for 28 days. Serum inorganic P fell from the initial 4.2 to 1.7 mg/100 ml in 28 days and total muscle P from 28.5 to 22.4 mmol/100 g fat-free DM. In muscle Na+ and Cl- increased and K+ decreased. Resting transmembrane electrical potential difference of muscle fell and muscle water content rose.

US$19.90

PMID: 947947

DOI: 10.1172/JCI108343


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