geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Considerations of aortic elastin chemistry in the genesis of the intimal plaque (Broad-Breasted White turkey)


, : Considerations of aortic elastin chemistry in the genesis of the intimal plaque (Broad-Breasted White turkey). Experimental and Molecular Pathology 31(3): 400-412

Fragmentation of internal and external elastic membranes occurs in the abdominal but not in the thoracic aorta of the Broad-Breasted White turkey during the early developmental period. In this early period, isolated elastin from the abdominal aorta contains more polar amino acid residues than elastin of the thoracic aorta. Additionally, the relative amount of a chemically unstable elastin cross-link, dehydrolysinonorleucine, is greater in the abdominal as compared to the thoracic aorta during the early developmental and adult periods. Cells of the abdominal aorta exposed to a higher arterial pressure and a greater rate of arterial pressure rise and in a region with a higher collagen:elastin ratio (reduced compliance to pulse-pressure-volume deformations) may synthesize a chemically unstable elastin which breaks down in regions of accentuated wall stress. Through these breaks of the internal elastic membranes, modified smooth muscle cells may migrate, proliferate and ultimately synthesize new elastin in forming the intimal plaque.

US$19.90

PMID: 510518

DOI: 10.1016/0014-4800(79)90040-6


Other references

Izhevskii, Ss, 1980: Entomophages of the Colorado potato beetle (Review) Leptinotarsa decemlineata biological control.1. Sel'skoe khoziaistvo za rubezhom: (7) 28-31

Abourbeh, G.; Shir, A.; Mishani, E.; Ogris, M.; Rödl, W.; Wagner, E.; Levitzki, A., 2012: PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors. Phage display has identified the dodecapeptide YHWYGYTPQNVI (GE11) as a ligand that binds to the epidermal growth factor receptor (EGFR) but does not activate the receptor. Here, we compare the EGFR binding affinities of GE11, EGF, and their polye...

Macara, I.G.; Baldarelli, R.; Field, C.M.; Glotzer, M.; Hayashi, Y.; Hsu, S-Chan.; Kennedy, M.B.; Kinoshita, M.; Longtine, M.; Low, C.; Maltais, L.J.; McKenzie, L.; Mitchison, T.J.; Nishikawa, T.; Noda, M.; Petty, E.M.; Peifer, M.; Pringle, J.R.; Robinson, P.J.; Roth, D.; Russell, S.E.Hilary.; Stuhlmann, H.; Tanaka, M.; Tanaka, T.; Trimble, W.S.; Ware, J.; Zeleznik-Le, N.J.; Zieger, B., 2002: Mammalian septins nomenclature. There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and dist...

Baaijens, AM., 2001: Lithophane leautieri settled in the Netherlands Lepidoptera Noctuidae Lithophane leautieri gevestigd in Nederland Lepidoptera Noctuidae. Adults of Lithophane leautieri have been found in The Netherlands since 1980 in increasing numbers, but it was not until 1998 when the first caterpillars were captured. Until then the species was considered to be a migrant (probably originating fr...

Spratt, J.S., 1992: Nonpalpable invasive breast cancer. Annals of Surgery 215(1): 89-89

Evans Martin, 1997: The geomorphic sensitivity of alpine-subalpine basins in the Cascade Mountains, British Columbia, Canada. Supplementi di Geografia Fisica e Dinamica Quaternaria (Testo Stampato) 3, Part 1: 160-161

Poorman, LH., 1981: Comments on two misunderstood fusinids (Gastropoda: Fasciolariidae) from the tropical eastern Pacific. Hundreds of fusinid specimens formerly referred to Fusinus dupetitthouarsi (Kiener, 1840) were examined; the presence of 2 radically different protoconchs and significant variations in the nepionic whorls and the teleoconchs were found. The materi...

Perrot J.; Young R.P.; Baker C., 1998: Earthquake rupture process in complex media using genetic algorithm based waveform inversion. Annales Geophysicae (1988) 16, Suppl

Morris, J.A.; Davidson, E.C.; Maidman, J.C.; Arce, J.J.; Brown, J.E.; Frazer, R., 1976: Sampling the fetoplacental circulation. I. The pregnant ovine. Intrauterine endoscopy (fetoscopy) was successfully accomplished in 26 specially prepared pregnant sheep at 85 to 110 days' gestational age, with the use of a conventional 2.7 mm. Hopkins straightforward wide-angle telescope (Stortz 27018A) e...

Gastaldelli, M.; Stefani, E.; Lettini, A.Anna.; Pozzato, N., 2011: Multiplexed typing of Mycobacterium avium subsp. paratuberculosis types I, II, and III by Luminex xMAP suspension array. Differentiation among types I, II, and III is the primary step in typing Mycobacterium avium subsp. paratuberculosis. We propose an innovative approach based on detection of gyrase B (gyrB) gene polymorphisms by suspension array technology, with h...