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Effect of the nutritional state on the synthetic activity involved in the microsomal chain elongation of fatty acids in rat liver. The role of cyclic AMP


, : Effect of the nutritional state on the synthetic activity involved in the microsomal chain elongation of fatty acids in rat liver. The role of cyclic AMP. Bollettino della Societa Italiana di Biologia Sperimentale 54(17): 1631-1637

Male rats weighing 200 to 250 g in groups of 4 were given a normal diet, kept without food for 48 h, kept without food for 48 h then given for the next 48 h a diet consisting of purified casein 30, starch 64, salt mixture 4, cellulose 2, choline chloride 0.1% and mixed vitamins, the same but during refeeding given intraperitoneally 6 mg dibutryl cyclic AMP and 2 mg theophylline at intervals of 8 h or the theophylline only in the injection. After 96 h the liver was removed.

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