+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A gene of the immunoglobulin H-chain cluster controls the murine antibody response to pneumococcal polysaccharide type 14

, : A gene of the immunoglobulin H-chain cluster controls the murine antibody response to pneumococcal polysaccharide type 14. Scandinavian Journal of Immunology 12(2): 155-158

Mice of various strains were immunized with pneumococcal polysaccharide type 14 (pneumo-14), and their anti-pneumo-14 antibodies were measured by the Farr test. Mice of strains BALB/c, ST/b, NZB and CBA (Ig allotypes a, e or j) had 300-1700 ng of antibody nitrogen per millilitre of serum on day 7. The corresponding values for C57BL/Ka, RF or AKR mice (allotypes b, c or d) were 40-300 ng/ml. Two families of congenic strains were tested, one with the C57BL and the other with the BALB/c background genome. Their response was either high or low depending on the VH genes, and other gene loci had little effect on the concentration of anti-pneumo-14 antibodies.


PMID: 6777868

DOI: 10.1111/j.1365-3083.1980.tb00052.x

Other references

Novak, P.; Vrba, L.; Matousek, J.; Patzak, J.; Fussy, Z., 2005: The establishment and screening of hop genomic and cDNA libraries for genes determining lupulin production. The analysis of in vivo expression of chalcone synthase (CHS) homologues at the RNA and protein levels in various phenotypes indicated the presence of fine regulatory factors involved in the determination of lupulin biosynthesis. For a detailed an...

Maier, T., 1998: Fibromyalgia (generalized tendomyopathy) in expert assessment. MEDAS-agencies are medical institutions within the Swiss Disability Insurance, which specialize in assessing the working capacity of candidates who apply for a disability pension. Degenerative and other chronic pain disorders of the musculoskeleta...

Schiewe, MC.; Bush, M. de Vos, V.; Brown, JL.; Wildt, DE., 1991: Semen characteristics, sperm freezing, and endocrine profiles in free-living wildebeest (Connochaetes taurinus) and greater kudu (Tragelaphus strepsiceros). Journal of Zoo and Wildlife Medicine, 221: 58-72

Heemeskerk F.M.J.; Schrama L.H.; Gianotti C.; Spierenburg H.; Versteeg D.H.G.; D.G.aan P.N.E.; Gispen W.H., 1990: 4 aminopyridine stimulates b 50 gap43 phosphorylation and tritiated noradrenaline release in rat hippocampal slices. In situ phosphorylation of the presynaptic protein kinase C substrate B-50 was investigated in rat hippocampal slices incubated with the convulsant drug 4-aminopyridine (4-AP). Phosphorylation of B-50 was significantly enhanced 1 min after the add...

Livshits, I.N., 1975: Efficacy of conservative therapy of radicular cysts of the jaw in various conditions of patient reactivity. Stomatologiia 54(3): 20=2-20=2

Abo E.D.hab, M.K.; E.G.orani, M.A.; E.B.noby, F.E., 1973: Effective control of bacterial scab for gladiolus. The effects of various fungicides and antibiotics on the growth of the pathogen, Pseudomonas marginata, were studied in vitro and the most effective chemicals were tested as pre-planting treatments. It is recommended that heavily infested soil be...

Thibault, J.L.; Valeyre, D.; Bladier, D.; Belin, C.; Salama, J.; Delaporte, P., 1996: A prospective study of cerebrospinal fluid angiotensin-converting enzyme in neurosarcoidosis. Neurology 46(2 SUPPL ): A299

Lakmichi, H.; Bakhtaoui, F.Zahra.; Gadhi, C.A.; Ezoubeiri, A.; E.J.hiri, Y.; E.M.nsouri, A.; Zrara, I.; Loutfi, K., 2010: Toxicity Profile of the Aqueous Ethanol Root Extract of Corrigiola telephiifolia Pourr. (Caryophyllaceae) in Rodents. Corrigiola telephiifolia Pourr. (Caryophyllaceae) is a Moroccan medicinal plant. Despite its popular usage, no study has been published concerning its toxicological profile. The acute toxicity of C. telephiifolia root extract was evaluated by givi...

Baati, S.; Mahfoudh, A.; Sahnoun, S.; Karray, A.; Karray, M.; Hachicha, M.; Tahri, N.; Krichen, M.S.; Triki, A., 1994: Caustic esophagitis in children: report of 34 cases. La Tunisie Medicale 72(6-7): 412-419

TILLOTSON.J.F.; McDONALD.J.R.; JANES.J.M., 1951: Synovial sarcomata. Journal of Bone and Joint Surgery. American Volume 33-A(2): 459-473