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A major autosomal gene effect on activity of glucose 6-phosphate dehydrogenase segregating between recombinant inbred lines of mice

, : A major autosomal gene effect on activity of glucose 6-phosphate dehydrogenase segregating between recombinant inbred lines of mice. Genetical Research 36(1): 91-97

The levels of erythrocyte glucose 6-phosphate dehydrogenase (G6PD), erythrocyte nicotinamide adenine dinucleotide phosphate (NADP) and Hb were measured in C57L/J and C57BL/6J mice and mice of their 4 recombinant inbred lines (LXB-1, LXB-2, LXB-3 and LXB-4). In both males and females , G6PD levels were significantly higher in C57BL/6J and LXB-3 mice than in the other 4 lines. Although Hb level varied significantly between lines, it was not significantly correlated with G6PD level.


PMID: 7439685

DOI: 10.1017/s0016672300019698

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