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Oxytocin and neurophysin in plasma and CSF during suckling in the guinea-pig


, : Oxytocin and neurophysin in plasma and CSF during suckling in the guinea-pig. Neuroendocrinology 34(1): 59-63

Cerebrospinal fluid (CSF) obtained from the cisterna magna of conscious unrestrained guinea pigs was assayed for oxytocin (OT), vasopressin (AVP) and neurophysin (NP). Basal concn. of OT and AVP were approx. 5 and 15 fmol/ml, resp. whereas NP concn. were considerably higher (around 1 pmol/ml); there were no significant differences between males, females and lactating females. In lactating females, simultaneous samples of blood and CSF were obtained during suckling episodes.

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PMID: 7057961


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