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The pharmacokinetics of fenbendazole and oxfendazole in cattle


, : The pharmacokinetics of fenbendazole and oxfendazole in cattle. Veterinary Research Communications 8(3): 187-194

The pharmacokinetics of fenbendazole and oxfendazole in cattle are described. The pharmacokinetics of oxfendazole were not significantly different when administered orally and by intra-ruminal injection. At a dose rate of 4.5 mg/kg, administered orally, fenbendazole gave rise to mean peak concentrations in plasma of fenbendazole and oxfendazole of 0.11 and 0.13 .mu.g/ml, respectively. Oral administration of oxfendazole, at 4.5 mg/kg body wt, gave rise to plasma peak concentrations of fenbendazole and oxfendazole of 0.10 and 0.20 .mu.g/ml, respectively. Following intra-ruminal administration of oxfendazole, the peak concentrations were 0.11 and 0.18 .mu.g/ml respectively.

US$19.90

PMID: 6495635

DOI: 10.1007/bf02214711


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