geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Comparison of two strategies for control of malaria within a primary health care programme in The Gambia


, : Comparison of two strategies for control of malaria within a primary health care programme in The Gambia. Lancet 1(8595): 1121-1127

Two drug strategies for the control of malaria in children aged 3-59 months have been compared in a rural area of The Gambia.sbd.treatment of presumptive episodes of clinical malaria with chloroquine by village health workers, and treatment combined with fortnightly chemoprophylaxis with 'Maloprim' (pyrimethamine/dapsone) which was also given by village health workers. Treatment alone did not have any significant effect on mortality or morbidity from malaria. In contrast, treatment and chemoprophylaxis reduced overall mortality in children aged 1-4 years, mortality from probable malaria, and episodes of fever associated with malaria parasitaemia. A high level of compliance with chemoprophylaxis was obtained and no harmful consequences of chemoprophylaxis were observed.

US$19.90

PMID: 2896957

DOI: 10.1016/S0140-6736(88)91949-6


Other references

Cunnah D.; Perry L.; Dacie J.A.; Grant D.B.; Lowe D.G.; Savage M.O.; Besser G.M., 1989: Bilateral testicular tumors in congenital adrenal hyperplasia a continuing diagnostic and therapeutic dilemma. Bilateral testicular tumours are a rare but well described complication of congenital adrenal hyperplasia (CAH). It can be extremely difficult to distinguish histologically between Leydig cell tumours and adrenocortical rest hyperplasia which may...

Kao, P.F.; Tzen, K.Y.; Lieu, S.R.; Lin, Y.C.; Ng, S.H., 1999: Development of a device for immobilization of head and correlation of functional-anatomical brain images. The excellent resolution of brain imaging modalities has important contributions in the diagnosis of brain diseases. However, involuntary movement by the patient may cause poor image quality. In this study, we developed a device to help keep a pat...

Tapper, J.B.; Giesecke, A.H., 1990: Spinal anaesthesia in a child with Job's syndrome, pneumatoceles and empyema. We present a case of acute bowel obstruction in an immunocompromised child, who also had lobar pneumonia and a giant unilateral pneumatocele. She was successfully managed with subarachnoid anaesthesia for exploratory laparotomy to relieve a coloni...

Naudo, P.; Laccourreye, O.; Weinstein, G.; Jouffre, V.; Laccourreye, H.; Brasnu, D., 1998: Complications and functional outcome after supracricoid partial laryngectomy with cricohyoidoepiglottopexy. We present a review of the postoperative course, complications, and functional outcome of 190 patients consecutively treated with supracricoid partial laryngectomy with cricohyoidoepiglottopexy. The average times until removal of the tracheostomy...

Albrecht, Jörg; Neuschulz, E.L.; Farwig, N., 2012: Impact of habitat structure and fruit abundance on avian seed dispersal and fruit predation. So far, it is poorly understood how differential responses of avian seed dispersers and fruit predators to changes in habitat structure and fruit abundance along land-use gradients may translate into consequences for the seed dispersal of associat...

Pinker, K.; Shitano, F.; Sala, E.; Do, R.K.; Young, R.J.; Wibmer, A.G.; Hricak, H.; Sutton, E.J.; Morris, E.A., 2017: Background, current role, and potential applications of radiogenomics. With the genomic revolution in the early 1990s, medical research has been driven to study the basis of human disease on a genomic level and to devise precise cancer therapies tailored to the specific genetic makeup of a tumor. To match novel thera...

Yurakhno, M.V., 1989: Flexobothrium microovatum sp. nov., gen. nov. (Cestoda, Diphyllobothriidae), a parasite of southern elephant seals. Flexobothrium microovatum gen. nov., sp. nov. from 3 of 5 Mirounga leonina in the Antarctic is described. Mature worms were present in the large intestine and immature worms in the small intestine; from 3 to 246 specimens/host were found. These wh...

Longo, E.; Santis, E.De.; Hussain, R.; van der Walle, C.F.; Casas-Finet, J.; Uddin, S.; Santos, A.Dos.; Siligardi, G., 2015: The effect of palmitoylation on the conformation and physical stability of a model peptide hormone. Peptides are ideal drug candidates due to their potency and specificity, but suffer from a short half-life and low membrane permeability. Acylation can overcome these limitations but the consequences to stability under different formulation condit...

Petrini, C., 2016: Is an opt-out organ donation system desirable? Comments on a new law. A law that introduces an opt-out system for organ donation has recently come into force in Wales. The debate surrounding the effectiveness and ethical acceptability of an opt-out system continues, though the available data have still not provided...

Buhler, P., 1987: Zur Strategie des Beutefangs der Nachtschwalben (Caprimulgidae). Journal fuer Ornithologie, 1284: 488-491