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Flavin catabolites: identification and quantitation in human urine

, : Flavin catabolites: identification and quantitation in human urine. American Journal of Clinical Nutrition 46(5): 830-834

Riboflavin is the primary flavin excreted in human urine but significant amounts of 7alpha-hydroxyriboflavin and lesser amounts of 8alpha-hydroxyriboflavin are present and reflect tissue microsomal oxidations. A newly found flavin catabolite of an 8alpha-sulfonyl type may reflect intake and/or turnover of such thioether-linked flavin as occurs in monoamine oxidase. Additionally, lesser amounts of 10-hydroxyethylflavin (indicative of intestinal microbial action on the vitamin) and traces of lumiflavin (arising from photodecomposition) constitute part of the remaining flavin, which acutely reflects level of intake. (author)


PMID: 3673930

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