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Metabolic rate measurements in males inspiring a high oxygen concentration compared to room air

, : Metabolic rate measurements in males inspiring a high oxygen concentration compared to room air. Nutrition Research 10(3): 247-254

The extent that high fractional in pired oxygen concentrations (FIO2) affect metabolic measurements was evaluated using indirect calorimetry. On each of three test days indirect calorimetry was performed twice in six subjects, first while subjects inspired an FIO2 of 0.6 (60% O2) and then room air (RA; FIO2 of 0.2093). The metabolic parameters obtained were minute ventilation (.ovrhdot.VE), oxygen consumption (.ovrhdot.VO2), and carbon dioxide production (.ovrhdot.VCO2). The resting energy expenditure (REE) was calculated from .ovrhdot.VO2 and .ovrhdot.VCO2 corrected for urinary nitrogen loss. Metabolic parameters were not statistically different between 60% O2 and RA over the three test days. At an FIO2 of 0.6, .ovrhdot.VE was 8.6 .+-. 0.6 L/min, .ovrhdot.VO2 was 270 .+-. 11 ml/min, .ovrhdot.VCO2 was 216 .+-. 11 ml/min and REE was 1850 .+-. 200 kcal/day compared to a .ovrhdot.VE of 8.6 .+-. 0.5 L/min, .ovrhdot.VO2 of 258 .+-. 14 ml/min, .ovrhdot.VCO2 of 209 .+-. 10 ml/min and REE of 1760 .+-. 225 kcal/day, respectively, while breathing RA. These results suggest that inspiring a high FIO2 does not significantly affect the metabolic measurements in spontaneously breathing subjects.


DOI: 10.1016/S0271-5317(05)80266-0

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