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Sensitivity of suckling rats to aflatoxin B1


, : Sensitivity of suckling rats to aflatoxin B1. Proceedings of the Japanese Association of Mycotoxicology ( 29): 31-32

The effects of aflatoxin B1 (af B1) on hepatocytes of fetus and suckling rats were studied electron microscopically. Until 4-d-old, af B1 did not cause any discernable change in the hepatocyte nucleoli. A decrease of the relative size of the nucleoli first appeared at the age of day 6. During the first 4 d after birth, the quantity of smooth endoplasmic reticulum (SER) as well as rough endoplasmic reticulum (RER) in the hepatocytes was less than that of the adult hepatocytes.

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