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Development of thyroxine 5' monodeiodinase activity in brown adipose tissue of young Zucker rats


, : Development of thyroxine 5' monodeiodinase activity in brown adipose tissue of young Zucker rats. Obesity in Europe 91 Proceedings of the 3rd European Congress on Obesity: 101-105

To determine whether the capacity of triiodothyronine production was altered in brown adipose tissue (BAT) of Zucker fa/fa rats, thyroxine 5'-deiodinase activity was measured in Fa/fa and fa/fa littermates from day 2 to day 30 after birth. In the early suckling period (from day 2 to day 16) the enzyme activity was significantly reduced in BAT of pre-obese compared with lean young.

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