+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Pathology of ovary, uterus, vagina and gonadotrophs of female mice fed on Zn-deficient diet

, : Pathology of ovary, uterus, vagina and gonadotrophs of female mice fed on Zn-deficient diet. Indian Journal of Experimental Biology 28(11): 1058-1065

Dietary Zn-deficiency in mature female mice for 6 weeks caused a retardation of ovarian growth characterized by lack of vesicular and Grafian follicles, degenerated corpus luteum, distorted cell membranes of granulosa cells with pycnotic nuclei, poor development of theca interna, inordinate accumulation of sudanophilic granules in theca interna and interstitial cells. The vagina and uterus did not exhibit cyclic changes in their cytoarchitecture as a result of the cessation of estrous cycle after 6 weeks of dietary treatment. They displayed wide spread degenerative changes in their myometrial and endometrial layers. The uterine glands appeared collapsed with little or no secretion. The vagina lacked cornification. Their gonadotrophs reacted positive to PAS, identical to the control group observed at diestrous stage. However, they did not display a negative reaction, characteristic of the gonadotrophs at estrous stage of the control group, examined even at an interval of 1 day for 6 days in succession. These results point towards the suspension of steroidogenesis inspite of intact gonadotrophs under Zn-deficiency condition.


PMID: 2283172

Other references

Skakun N.P.; Drogovoz S.M., 1970: The effect of total x ray irradiation on the synthesis of bile acids in albino female rats chromatographic study. Byulleten' Eksperimental'noi Biologii i Meditsiny 70(9): 40-41

Adamkiewicz, V.W.; Uhthoff, H.K., 1958: Experimental x-ray angiography using carbonyl iron. The animal or organ is injected intra-arterially, by a syringe and needle, with a 60% w/v suspension of "Carbonyl Iron", (Antara Chemicals, N.Y.), in water containing 1% w/v carboxymethylcellulose, 0.1% v/v "Tween 80" and 0.1%...

Khaleel Raz; Reddell Donald L., 1986: MOC solutions of convective-dispersion problems. Ground Water 24(6): 798-807

Lu, S.; Guo, X.; Zhao, P., 2012: Effect of Ginkgo biloba extract 50 on immunity and antioxidant enzyme activities in ischemia reperfusion rats. The aim of the study was to investigate the effect of Ginkgo biloba extract 50 (GBE50), a well-known natural antioxidant, against immunity and antioxidant enzyme activities in ischemia reperfusion (IR) rats. Rats were then divided into six groups...

Mamedov, A.M.; A'lber, V.O.; Podo'lko, G.S.; Kosareva, L.B., 1989: Stability of the somatic and autonomic nervous systems during occupational activities. The paper deals with some experience gained in the use of systemic quantitation of behavior for diagnosing the functional status of a working man. Comparing the indices of the somatic and autonomic nervous system with the stage and end resultant p...

Valla, P.G.; Shuster, D.L.; van der Beek, P.A., 2011: Significant increase in relief of the European Alps during mid-Pleistocene glaciations. Nature Geoscience 4.10

Vanhoffen, E., 1903: Die craspedoten Medusen der deutschen Tiefsee-Expedition 1898-1899. I Trachymedusen T c, 55-86

Allen, AA., 1992: On Bagous arduus Sharp and B. rudis Sharp (Col.: Curculionidae). Entomologist's Record and Journal of Variation, 1047-8: 199-201

Gloe, P., 1987: Zum Kleptoparasitismus der Dreizehenmowe (Rissa tridactyla) an Brandseeschwalben (Sterna sandvicensis). Seevoegel 8(1): 18

Yasui, T.; Kasamatsu, N.; Seto, T.; Shinozuka, N.; Nakamura, A.; Hashizume, I., 2006: A case of Ortner syndrome caused by primary pulmonary hypertension. Left vocal cord palsy is a rare complication of pulmonary hypertension (also known as Ortner syndrome). Here we report a case of a patient with Ortner syndrome caused by primary pulmonary hypertension (PPH). The patient was a 28-year-old woman, wh...