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Plasmodium falciparum: induction of biologically active antibodies to gp195 is dependent on the choice of adjuvants

, : Plasmodium falciparum: induction of biologically active antibodies to gp195 is dependent on the choice of adjuvants. Experimental Parasitology 75(1): 155-157

It was investigated whether the adjuvant formulation based on the synthetic immunomodulators B30-MDP and LA-15-PH, can influence the induction of biologically active mouse anti-gp195 (the major merozoite surface protein of P. falciparum) antibodies. Mouse sera were obtained from a previous study in which C57Bl/10 SnJ mice were immunized ip 4 times at 21-day intervals with purified gp195 in different adjuvant formulations based on B30-MDP and LA-15-PH.


PMID: 1639161

DOI: 10.1016/0014-4894(92)90131-s

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