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Stimulatory effects of recombinant follicle-stimulating hormone on Leydig cell function and spermatogenesis in immature hypophysectomized rats

, : Stimulatory effects of recombinant follicle-stimulating hormone on Leydig cell function and spermatogenesis in immature hypophysectomized rats. Endocrinology 129(4): 1926-1932

Immature rats were hypophysectomised and implanted with osmotic minipumps which released 8 IU recombinant FSH or 18 IU purified human pituitary FSH (hpFSH) per day; control animals received a vehicle. After 7 days of treatment, testes weight increased in the recombinant FSH- and hpFSH-treated animals by 2.3- and 2.5-fold resp. compared with that of controls.


PMID: 1915076

DOI: 10.1210/endo-129-4-1926

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