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The cell content of peritoneal exudates following the injection of neutral thiol protease into guinea pigs

, : The cell content of peritoneal exudates following the injection of neutral thiol protease into guinea pigs. Journal of Parasitology 77(4): 635-637

The cell content of the peritoneal exudate was examined 4 days after an intraperitoneal injection of glycogen in uninfected and Paragonimus westermani-infected guinea pigs. In uninfected animals a reduction in macrophage count and an accumulation of granulocytes in the exudate were observed at 3 and 6 hr after an intraperitoneal injection of purified neutral thiol protease from P. westermani metacercariae. No such effect occurred after the enzyme was injected into infected animals. At 9 hr after enzyme injection, vacuoles were found in the cytoplasm of macrophages in uninfected animals.


PMID: 1865274

DOI: 10.2307/3283174

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