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Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form

, : Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form. Journal of Biological Chemistry 267(3): 1888-1895

Leishmania sp. protozoa contain an abundant surface protease (gp63) that is important for the virulence of the parasite. found that the average amount of gp63 expressed by Leishmania donovani chagasi promastigotes increases 6-11-fold as they develop from a less infectious form in logarithmic phase to a highly infectious form during stationary phase of cultivation in vitro.


PMID: 1370484

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