geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Breast milk from mothers of children with newly developed atopic eczema has low levels of long chain polyunsaturated fatty acids


, : Breast milk from mothers of children with newly developed atopic eczema has low levels of long chain polyunsaturated fatty acids. Journal of Allergy & Clinical Immunology 91(6): 1134-1139

Background: Infants at risk of atopic dermatitis have lower than normal levels of long chain polyunsaturated fatty acids. These fatty acids are normally present in substantial quantities in human breast milk. Methods: Because of the equivocal evidence concerning the ability of breastfeeding to delay the onset or reduce the severity of atopic dermatitis, we have analyzed the fatty acid composition of breast milk from the mothers of children with newly developed disease with the use of gas chromatography. Results: Breast milk lipids from mothers of children with newly developed atopic dermatitis had increased proportions of linoleic acid and significantly decreased proportions of its long chain polyunsaturated derivatives compared with a control group. The ratio of linoleic acid to the sum of its metabolites, gamma-linolenic acid, dihomo-gamma-linolenic acid, and arachidonic acid was 11.78 in the atopic group and 9.02 in the control group (p lt 0.01). Conclusions: These results are consistent with previous findings of an abnormal fatty acid status in atopic subjects and may account for some of the inconsistent results from studies of the effect of breastfeeding on the subsequent development of atopic dermatitis. We conclude that further studies to examine the effects of supplementation of the diet of breastfeeding mothers with long chain polyunsaturates should be done.

US$19.90

PMID: 8509576

DOI: 10.1016/0091-6749(93)90315-7


Other references

Emil Witschi, 1931: Studies on sex differentiation and sex determination in amphibians V Range of the cortex-medulla antagonism in parabiotic twins of Ranidae and Hylidae. Journal of Experimental Zoology Part A Ecological Genetics and Physiology 58(1): 113-145

Duenhaupt A.; Lang S.; Wagner F., 1991: Characterization and enrichment of the lipase of pseudomonas cepacia dsm 50181. Fett Wissenschaft Technologie 93(12): 470

Rabiner, D.L.; Murray, D.W.; Rosen, L.; Hardy, K.; Skinner, A.; Underwood, M., 2010: Instability in teacher ratings of children's inattentive symptoms: implications for the assessment of ADHD. To examine the cross-grade stability of clinically elevated teacher ratings of inattentive symptoms in 3 samples of elementary schoolchildren. Samples 1 and 2 included 27 first graders and 24 fourth graders, respectively, identified based on clini...

Weinstein-Oppenheimer, C.; Steelman, L.S.; Algate, P.A.; Blalock, W.L.; Burrows, C.; Hoyle, P.E.; Lee, J.T.; Moye, P.W.; Shelton, J.G.; Franklin, R.; McCubrey, J.A., 2000: Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells. The effects of deregulated Raf activation on the growth and differentiation of hematopoietic cells were investigated. The cytokine-dependent murine myeloid FDC-P1 and human erythroleukemic TF-1 cell lines were transformed to grow in response to de...

Ask-Upmark, E., 1969: The sign of the "bloated glove" ("pudgy glove"). Folia Clinica Internacional 19(4): 225-229

Baker, W.H.; Mahler, D.K.; Foldes, M.S.; Michelini, M.A.; Hayes, A.C.; Littooy, F.N.; Greisler, H.P., 1986: Pneumatic compression devices for prophylaxis of deep venous thrombosis (DVT). A pneumatic compression device was applied to 155 patients with a normal Doppler venous examination who underwent a general surgical procedure of at least 1 hr in duration. One hundred fifty-three patients had neither PE nor DVT clinically or by D...

Sümegi, B.; Gyócsi, L.; Alkonyi, I., 1980: Interaction between the pyruvate dehydrogenase complex and citrate synthase. Kinetic studies of the individual reaction of pig heart pyruvate dehydrogenase complex (pyruvate dehydrogenase (pyruvate:lipoamide oxidoreductase (decarboxylating and acceptor-acetylating), EC 1.2.4.1); dihydrolipoamide reductase(NAD+) (NADH:lipoa...

Broyer, M.; Berger, R., 1968: Cystinuria--familial lysinuria. La Presse Medicale 76(16): 754-754

Sun H Y., 1990: Permian fusulinids from the dasuangou formation in yanbian county jilin. Fusulinids from the lower Permian Dasuangou Formation in Jilin, Yanbian County described and illustrated in this paper comprise 6 genera (Parafusulina, Chusenella, Cuniculenella, Pseudodoliolina, Metadoliolina, Neomisellina) and 14 species (P. reg...

Williams I.P.; Mcgavin C.R., 1980: Cortico steroids in chronic airway obstruction can the assessment by the patient be ignored. To examine the methods of assessing the response of patients with chronic airway obstruction to corticosteroids, 20 patients received 1 wk of placebo tablets, followed by 3 wk of prednisolone 30 mg daily. Subjective benefit was assessed by a visua...