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Comparative efficacies of cilofungin (Ly121019) and amphotericin B against disseminated Candida albicans infection in normal and granulocytopenic mice

, : Comparative efficacies of cilofungin (Ly121019) and amphotericin B against disseminated Candida albicans infection in normal and granulocytopenic mice. Antimicrobial Agents and ChemoTherapy 37(4): 729-736

The efficacies of cilofungin (LY121019) and amphotericin B in the treatment of disseminated candidosis in normal and neutropenic mice were compared. In mice infected with 2 x 106 colony forming units (CFU) of C. albicans, treatment with cilofungin in twice-daily doses of 25 or 35 mg/kg of body wt by intraperitoneal injection for 10 d gave survival rates of 83 and 90%.


PMID: 8494367

DOI: 10.1128/aac.37.4.729

Other references

L.R.ngqiang; Kong Defang; Nie Dexing, 1990: Study on mechanical property of fault gouge under ground stress environment. Congres International Association International de Geologie de l'Ingenieur = International Congress International Association of Engineering Geology: ges 419-424. 1990.

Wagner, HP.; Coomans, HE., 1990: Review of the Perotrochus africanus - complex, with a note on the nomenclature of the Western Australian species (Mollusca, Gastropoda; Pleurotomariidae). Gloria Maris, 293: 41-52

Fregnani, L., 1968: Rehabilitative treatment of infantile cerebropathies. L' Arcispedale S. Anna di Ferrara 21(1): 83-94

Munro, Ian C., 2001: Principle of substantial equivalence. The first step in evaluating a genetically modified food is to assess the safety of the genetic material being introduced. The gene insert needs to be characterized and the genetic material must not be derived from a pathogenic, toxicogenic or all...

Saksena, S.; Gill, R.; Tyagi, S.; Alrefai, W.A.; Ramaswamy, K.; Dudeja, P.K., 2002: Involvement of 5-HT3/4 receptor subtypes in the serotonin induced inhibition of Cl-/OH- exchange activity in Caco-2 cells. Gastroenterology 122(4 Suppl 1): A 539, April

Khan, O.A.; Rawes, J.; Calabrese, V.P.; Devries, G.H., 1995: Presence of antibodies to the axolemma in the cerebrospinal fluid of multiple sclerosis patients presenting with acute exacerbations. Neurology 45(4 SUPPL 4): A165

Sadej, R.; Spychala, J.; Skladanowski, A.C., 2006: Expression of ecto-5'-nucleotidase (eN, CD73) in cell lines from various stages of human melanoma. Ecto-5'-nucleotidase is a GPI-anchored enzyme localized in cell membrane lipid rafts. Although it is highly expressed in many tumour cells, its specific function during tumorigenesis is unclear. We have found that, among different melanoma ce...

Johnson, M.T.J.; Lajeunesse, M.J.; Agrawal, A.A., 2006: Additive and interactive effects of plant genotypic diversity on arthropod communities and plant fitness. Recent research suggests that genetic diversity in plant populations can shape the diversity and abundance of consumer communities. We tested this hypothesis in a field experiment by manipulating patches of Evening Primrose (Oenothera biennis) to...

Van Engelen B.G.M.; Strengers P.F.W.; Renier W.O.; Weemaes C.M.R., 1991: Study of immunological aspects of therapy resistant childhood epilepsy effects of therapy with intravenous immunoglobulin. Imbach, P (Ed ) Immunotherapy With Intravenous Immunoglobulins; Conference, Interlaken, Switzerland, May 6-9, 1990 Xx+484p Academic Press Ltd : London, England, Uk; San Diego, California, Usa Illus 467-468

Sen, P.K.; Banerjee, S.P., 1960: Ratoon tillers, culm branching and vegetative ear in rice. Indian Agric 4(1): 63-66