geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

GnRH-dependent and -independent components of FSH secretion after acute treatment of anoestrous ewes with ovine follicular fluid and a GnRH antagonist


, : GnRH-dependent and -independent components of FSH secretion after acute treatment of anoestrous ewes with ovine follicular fluid and a GnRH antagonist. Journal of Reproduction and Fertility 98(2): 591-595

Gonadotrophin and inhibin concentrations were measured in anoestrous ewes after acute treatment with either saline, ovine follicular fluid (oFF), GnRH antagonist, or oFF and GnRH antagonist in combination. The increase in mean LH concentrations observed in ewes treated with oFF alone, was not seen in either of the groups treated with GnRH antagonist, in which LH pulsatility was completely inhibited. This result suggests that the LH rebound that follows follicular fluid treatment is GnRH dependent. Blockade of GnRH had no effect on the suppression of FSH seen after follicular fluid injection, indicating that this component of FSH secretion is independent of short-term GnRH input. After this initial suppression, a rebound release of FSH was seen in the group treated with oFF alone. The addition of GnRH antagonist appeared to decrease the rebound, suggesting that this rebound release of FSH may have a GnRH-dependent component. Inhibin concentrations in both oFF-treated groups increased after oFF injection and then declined to pretreatment values. However, a second rise in inhibin concentration, concomitant with the FSH rebound in ewes receiving oFF alone, was seen in the group treated with oFF and GnRH antagonist. As this rise in endogenous inhibin concentration could also act to suppress the rebound release of FSH, it cannot be conclusively proved from this study that GnRH input is required for the generation of the rebound release of FSH after treatment with oFF.

US$19.90

PMID: 8410829

DOI: 10.1530/jrf.0.0980591


Other references

Bień, A.; Rzońca, E.; Iwanowicz-Palus, Gżyna.; Lecyk, U.; Bojar, I., 2017: The quality of life and satisfaction with life of women who are childless by choice. <b>Objective</b>. The study attempts to identify and analyze factors affecting the quality of life and satisfaction with life of women who are childless by choice. <b>Materials and method</b>. The research instruments used...

Macisaac H.J.; Gilbert J.J., 1990: Does exploitative or interference competition from daphnia limit the abundance of keratella in loch leven scotland uk? a reassessment of may and jones 1989. Journal of Plankton Research 12(6): 1315-1322

Hoffman, M., 2003: A cell-based model of coagulation and the role of factor VIIa. Our cell-based model of haemostasis replaces the traditional 'cascade' hypothesis, and proposes that coagulation takes place on different cell surfaces in three overlapping steps: initiation, amplification, and propagation. In highlighti...

Daniels, JC., 1983: Hyalophora cecropia problems: the outdoor solution. Exotic Entomology Group Newsletter, 4: 99

Wyller, T.B.; Korsmo, G.; Gadeholt, G., 1991: Dependence on carisoprodol (Somadril)? A prospective withdrawal study among prisoners. Carisoprodol (Somadril) was gradually withdrawn for a fortnight in nine male prisoners who had been taking daily doses of from 700 to 2,100 mg for at least nine months. The patients were assessed clinically during the withdrawal period, with speci...

Tyler, L.W.; Matossian, K.; Todd, R.; Gallagher, G.T.; White, R.R.; Wong, D.T., 2000: Eosinophil-derived transforming growth factors (TGF-alpha and TGF-beta 1) in human periradicular lesions. Inflammatory mediators of periradicular lesions are poorly understood. Transforming growth factors-alpha and -beta 1 (TGF-alpha and TGF-beta 1) have been linked with the cellular processes for both soft and hard tissue wound healing. The purpose o...

Thomas, C.B., 1976: Precursors of premature disease and death. The predictive potential of habits and family attitudes. The youthful habits and family attitudes of medical students who later developed or died from one of five disease states were different from those of healthy classmate controls to begin with. In medical school, the total disorder group had signifi...

Sun, H.; Yang, Y.; Shao, H.; Sun, W.; Gu, M.; Wang, H.; Jiang, L.; Qu, L.; Sun, D.; Gao, Y., 2017: Sodium Arsenite-Induced Learning and Memory Impairment Is Associated with Endoplasmic Reticulum Stress-Mediated Apoptosis in Rat Hippocampus. Chronic arsenic exposure has been associated to cognitive deficits. However, mechanisms remain unknown. The present study investigated the neurotoxic effects of sodium arsenite in drinking water over different dosages and time periods. Based on re...

D.R.Driguez.E.; D.A.Gul.D.L.On.H., 1953: Seminar on nursing care in communicable diseases. Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau 34(1): 62-67

Dailey, R.N.; Montgomery, D.L.; Ingram, J.T.; Siemion, R.; Vasquez, M.; Raisbeck, M.F., 2008: Toxicity of the lichen secondary metabolite (+)-usnic acid in domestic sheep. Toxicity following ingestion of the vagrant, foliose lichen Xanthoparmelia chlorochroa was identified as the putative etiology in the death of an estimated 400-500 elk on the Red Rim-Daley Wildlife Habitat Management Area in Wyoming during the win...