geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents


, : Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents. International Journal of Pharmaceutics (Amsterdam) 86(2-3): 193-199

The effects of the cationic, non-antibiotic antimicrobial agents chlorhexidine gluconate, dequalinium chloride, cetrimide and cetylpyridinium chloride on the adherence of Candida albicans blastospores (MEN and oral clinical isolates, exponential and stationary growth phases) to human buccal epithelial cells in vitro were examined using light microscopy. All agents expressed significant anti-adherence activities at concentrations both greater and less than the minimum inhibitory concentration. In all cases, the anti-adherence effects were observed following treatment (30 min, 37 degree C) of either buccal epithelial cells or blastospores. In addition, the majority of treatments significantly increased the number of buccal epithelial cells free from adherent C. albicans. These observations may be useful in the prophylaxis of oral candidosis in prone individuals.

US$19.90

DOI: 10.1016/0378-5173(92)90197-a


Other references

Palmieri, L.; Berns, D.; Kraemer, R.; Eikmanns, M., 1996: Threonine diffusion and threonine transport in Corynebacterium glutamicum and their role in threonine production. Transmembrane threonine fluxes (i.e., uptake, diffusion, and carrier-mediated excretion) all contributing to threonine production by a recombinant strain of Corynebacterium glutamicum, were analyzed and quantitated. A threonine-uptake carrier that...

Gordillo, G.M.; Biswas, A.; Khanna, S.; Pan, X.; Sinha, M.; Roy, S.; Sen, C.K., 2014: Dicer knockdown inhibits endothelial cell tumor growth via microRNA 21a-3p targeting of Nox-4. MicroRNAs (miR) are emerging as biomarkers and potential therapeutic targets in tumor management. Endothelial cell tumors are the most common soft tissue tumors in infants, yet little is known about the significance of miR in regulating their grow...

Muntner, S.; Maimonides, 1968: Maimonides' treatise on asthma. Diseases of the Chest 54(2): 128-132

Mayo, D.J.; Burton, D., 1998: The in vitro physiology of melanophores associated with integumentary patterns in winter flounder (Pleuronectes americanus). The ocular (upper) surface of winter flounder (Pleuronectes americanus) possesses a pattern of cryptic dark bands and white spots, and a general background component, with melanophores under adrenergic neural control. In vitro the small dermal mel...

E.D.soky, A.E.H.mid; Delpy, D.T.; Davidson, B.R.; Seifalian, A.M., 2001: Assessment of hepatic ischaemia reperfusion injury by measuring intracellular tissue oxygenation using near infrared spectroscopy. Aims/Background: Hepatic ischaemia/reperfusion (I/R) injury is a major cause of liver damage during liver surgery and transplantation. The relationship between the severity of I/R injury and the degree of intracellular hypoxia has not been investi...

Uri, N.; Gill, M., 1990: The agricultural demand for natural gas and liquefied petroleum gas in the United States. Journal of energy and developmentng 15(2): 257-273

Murayama N.; Ishiko N., 1982: Cortical evoked potentials associated with subjective assessments of tactile and noxious stimuli in man. Journal of the Physiological Society of Japan 44(8-9): 395

Umekita, T.; Yamamoto, M., 1988: Analysis of the results of tuberculin reactions among primary and middle school students in K city, Kagoshima Prefecture, with special emphasis on the comparison of the intensity of tuberculin hypersensitivity in repeated tuberculin tests. Kekkaku 63(2): 93-99

Katz, N., 1994: Role of invasive procedures in chronic pain management. SCID mice injected with coisogenic CD4+/CD45RBhi lymph node T cells from normal donors develop a wasting disease that is due to hyperplasia of the intestinal epithelium. SCID mice injected with purified lymph node CD4+ T cells or CD4+/CD45RBlo T c...

Hecker, A.; Hasan, S.H.; Neumann, F., 1980: Disturbances in sexual differentiation of rat foetuses following spironolactone treatment. Pregnant rats were treated with 40 mg spironolactone (sp) po from the 13th to the 21st day p.c. The foetuses were prepared and histologically examined on day 22. The male foetuses showed distinct signs of feminization especially of the external ge...