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Using brine shrimp as a drug carrier for therapeutic applications in aquaculture


, : Using brine shrimp as a drug carrier for therapeutic applications in aquaculture. Aquacultural Engineering 13(4): 301-309

A method is described to introduce water-insoluble drugs into brine shrimp nauplii (BSN). The uptake of drug by brine shrimp may be modeled as a batch adsorption process; in this way, one can calculate the dosage required for a given population of BSN. The results of this study show that a drug can be loaded into BSN at concentrations up to 9 mu-g per nauplius. Such concentration is high enough to fulfill the recommended dosage for an adequate treatment of BSN-feeding fish or shrimp larvae. Results are also presented on the loss of drug upon the transfer of larvae from medicated water to drug-free water.

US$19.90

DOI: 10.1016/0144-8609(94)90017-5


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