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Effects of serum on lymphokines producing capabilities of CD8+ T cells


, : Effects of serum on lymphokines producing capabilities of CD8+ T cells. Korean Journal of Veterinary Research 34(3): 441-446

The responsiveness of CD8+ T cell sub populations according to serum-containing and serum-free conditions was investigated. Cells were freshly isolated from the spleen of mature adult BALB/C mice between 13-20 weeks of age. In serum-free conditions CD8+ T cells produced small amounts of IL-2 and significant amounts of IFNr following activation when compared to those in conditions containing serum.

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