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Azole antifungal agents: emerging and inherent resistance

, : Azole antifungal agents: emerging and inherent resistance. Current Opinion in Infectious Diseases 8(6): 424-427

The development of resistance to azole antifungals in yeasts is discussed, including resistance of Candida albicans to fluconazole, management of resistance, resistance in non-albicans Candida spp., mechanisms of resistance and fluconazole resistance in Cryptococcus neoformans.


DOI: 10.1097/00001432-199512000-00004

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Takeda, K.; Yamawaki, K.; Hatakeyama, N., 2002: 3 + 2] Annulation of beta-heteroatom-substituted alpha,beta-unsaturated acylsilanes with methyl ketone enolates: scope and investigation of the reaction course. A new route to (Z)-beta-silylacryloylsilanes 10 and the improved conditions for the [3 + 2] annulation using 10 and alkyl methyl ketone enolates are reported. Also, details of investigations defining a reaction course of the [3 + 2] annulation usi...