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Development of subchondral cystic lesions after articular cartilage and subchondral bone damage in young horses


, : Development of subchondral cystic lesions after articular cartilage and subchondral bone damage in young horses. Equine Veterinary Journal 28(3): 225-232

The objective of this study was to determine if damage to the articular cartilage alone or articular cartilage plus subchondral bone of the distal medial femoral condyle of young, exercised horses resulted in the formation of subchondral cystic lesions. Twelve Quarter Horses (age 1-2 years), free of clinical and radiographic signs of osteochondrosis and lameness were used. In 6 horses (Group 1), a 15 times 1 mm linear full thickness defect in the articular cartilage was made arthroscopically on the weightbearing surface of the distal aspect of the medial femoral condyle. In the other 6 horses (Group 2), a 15 times 3 mm full thickness elliptical cartilage defect was made, followed by burring a 5 mm diameter, 4 mm deep hole into the subchondral bone. Three weeks after surgery, all horses were hand walked and trotted for 2 weeks and then exercised for 6 min daily, 5 days a week for the next 14 weeks on a treadmill. They were then turned onto a small paddock for 6 weeks (6 months total). The development of subchondral cystic lesions was determined using radiography. Bone activity in the femoral condyle was monitored with nuclear scintigraphy. All horses that developed subchondral cystic lesions radiographically were subjected to euthanasia for gross and histological examination of the lesions. No subchondral cystic lesions and no clinical abnormalities were detected in the horses in Group 1. Subchondral cystic lesions developed radiographically in 5 of 6 horses in (Group 2). Scintigraphic findings of horses with subchondral cystic lesions were inconsistent. Histological examination of lesions revealed variable quantities of fibrous connective tissue, fibrocartilage and bone, with evidence of bone remodelling adjacent to the subchondral cystic lesion. The results suggest that damage to articular cartilage plus subchondral bone, but not articular cartilage alone, of the distal medial femoral condyle may lead to the development of subchondral cystic lesions. These findings indicate that all subchondral cystic lesions in horses may not be osteochondrosis-type lesions and that trauma to weightbearing articular surfaces of young horses may be a predisposing factor.

US$19.90

DOI: 10.1111/j.2042-3306.1996.tb03777.x


Other references

Kuo, M.L.; Arganbright, D.G., 1980: Cellular distribution of extractives in redwood and incense cedar. I. Radial variation in cell-wall extractive content. A method, based on rate of extraction, for determining the proportion of total extractives that is located in the cell walls. The radial variation of cell wall extractives in the heartwood of Sequoia sempervirens and Libocedrus decurrens and the v...

Weniger, P.; Schwarzbauer, J.; Littke, R., 2008: Evaluation of a possible application of organic geochemical and stable carbon isotope analysis of carboxylic acids in late Paleozoic coals for paleoenvironmental analyses. Schriftenreihe der Deutschen Gesellschaft fuer Geowissenschaften 60: 350

Bahulikar, A.V.; Joshi, J.N., 2006: Laryngopharyngeal dysthesia (LPD) in oxaliplatin infusion (OXLP). Journal of the Association of Physicians of India 54: 667-667

Chaudhry, S.Ashraf.; Khan, M.Tawab.; Khan, M.Khurram.; Shon, T., 2016: A Multiserver Biometric Authentication Scheme for TMIS using Elliptic Curve Cryptography. Recently several authentication schemes are proposed for telecare medicine information system (TMIS). Many of such schemes are proved to have weaknesses against known attacks. Furthermore, numerous such schemes cannot be used in real time scenario...

Hou, J.; Liu, S.; Ma, Z.; Lang, X.; Wang, J.; Wang, J.; Liang, Z., 1991: Effects of gynostemma pentaphyllum makino on the immunological function of cancer patients. Journal of Traditional Chinese Medicine 11(1): 47-52

Galbraith G.M.P.; Thiers B.H.; Vasily D.B.; Fudenberg H.H., 1984: Immunological profiles in alopecia areata. Cell-mediated immunity and auto-immune phenomena were investigated in 60 patients with active alopecia areata of various degrees of severity. Serum auto-antibodies to thyroid antigens were detected in 23 patients. Examination of T-lymphocyte popul...

Yakimoff, W.L., 1935: Sur la premunition par les especes do piroplasmidos, Repartition geographique du FranYaiella caucasica Yakimoff et Bolawine 1926. Annales de la Societe Belge de Medecine Tropicale, 15: 291-294

Seidenfeld, J.; Barnes, D.; Block, A.L.; Erickson, L.C., 1987: Comparison of DNA interstrand cross-linking and strand breakage by 1,3-bis(2-chloroethyl)-1-nitrosourea in polyamine-depleted and control human adenocarcinoma cells. Recent evidence from our laboratory and from others suggested that pretreatment with alpha-difluoromethylornithine (DFMO) sensitizes some human and rodent tumor cell lines to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Many human tumor cells are...

Einarsson, Hermann, 1960: The fry of sebastes in Icelandic waters and adjacent seas. Stramin-net material collected by Danish and Icelandic research ships 1903-1939 and 1948-1952 from 1787 stations, situated mainly in Icelandic waters and the Irminger Sea. Echo-records from the area south and west of Iceland during 1954-1958 were...

Johnson, J.R.; Murray, A.C.; Sullivan, M.; Snippes, P.; Smith, K.E., 2002: Isolation of nalidixic acid-resistant extraintestinal pathogenic Escherichia coli from retail chicken products. Background: Fluoroquinolone use in poultry production selects for quinolone-resistant gram-negative bacilli. However, although nalidixic acid-resistant (NAR) E. coli can be recovered from 40% of retail chicken products, whether such isolates repre...