geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Chlorophyll and chromosome breakage


, : Chlorophyll and chromosome breakage. Mutation Research 360(3): 187-191

Increased consumption of green vegetables in the diet has been associated with protection against carcinogenic effects and related mutagenic and clastogenic (chromosome breaking) activity of genotoxic agents. Chlorophyll, present in all green plant parts, has been suggested to be a major protective factor in the process. We have, however, observed that while a crude aqueous extract of Indian spinach leaf significantly reduced genotoxic effects, chlorophyll alone was ineffective. On the other hand, chlorophyll, both as an aqueous extract from the leaf and in a purified commercial form, induced a significantly high frequency of chromosome breaks in bone marrow cells of mice on oral administration. The crude aqueous extract of the leaf was non-toxic. The protective activity of the crude leaf extract may be attributed to the total effect of the interaction between different components, in which the clastogenicity of chlorophyll has been neutralized.

US$19.90

PMID: 8692218

DOI: 10.1016/s0165-1161(96)90016-3


Other references

Sideris E.; Yokochi K.; Vanhelder T.; Coceani F.; Olley P.M., 1982: Effects of prostaglandin d 2 on the fetal circulation of the lamb. Pediatric Research 16(4 PART 2): 308A

Newton, R.C., 1919: A Case of Enlarged Thymus Gland: And Some Remarks on Status Lymphaticus. Transactions of the American Climatological and Clinical Association. American Climatological and Clinical Association 35: 271-285

Rosenberg, V.; Rudick, J.; Robbiou, M.; Dreiling, D.A., 1975: Pancreatic exocrine secretion during and after pregnancy. Pancreatic secretion was measured in 8 dogs with Thomas duodenal and gastric fistulae during pregnancy, corresponding to the third trimester in man, during the puerperium and several months after whelping. The volume and bicarbonate concentration...

Luo, L.; Cai, B.; Liu, F.; Hu, X.; Wang, L., 2012: Association of Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) C1858T gene polymorphism with susceptibility to autoimmune thyroid diseases: a meta-analysis. Results from studies on the association of PTPN22 C1858T polymorphism with AITD risk are conflicting, we thereby perform this meta-analysis to derive a more precise effect on this possible association. Two investigators independently searched the...

Del Piccolo, L.; Putnam, S.M.; Mazzi, M.Angela.; Zimmermann, C., 2004: The biopsychosocial domains and the functions of the medical interview in primary care: construct validity of the Verona Medical Interview Classification System. Factor analysis (FA) is a powerful method of testing the construct validity of coding systems of the medical interview. The study uses FA to test the underlying assumptions of the Verona Medical Interview Classification System (VR-MICS). The relat...

Gabbett, T.J.; Jenkins, D.G., 2011: Relationship between training load and injury in professional rugby league players. To investigate the relationship between training load and injury in professional rugby league players; Prospective cohort study; Seventy-nine professional rugby league players (mean±SD age, 23.3±3.8 years) participated in this four-year study. A...

Okada, T.; Sato, Y.; Iwata, K.; Iwata, F.; Hara, M.; Kim, H.; Fuchigami, S.; Fuchigami, T.; Harada, K.; Okuni, M.; Ryo, S., 1994: Relationship between fat distribution and atherosclerotic variables in healthy schoolchildren Results of a study in the Susono area. Nihon University Journal of Medicine 36(5): 207-212

Winter, K.; Foster, J.G.; Schmitt, M.R.; Edwards, G.E., 1982: Activity and quantity of ribulose bisphosphate carboxylase-and phosphoenolpyruvate carboxylase-protein in two Crassulacean acid metabolism plants in relation to leaf age, nitrogen nutrition, and point in time during a day/night cycle. Activity of ribulose 1,5-bisphosphate (RuBP) carboxylase in leaf extracts of the constitutive Crassulacean acid metabolism (CAM) plant Kalanchoe pinnata (Lam.) Pers. decreased with increasing leaf age, whereas the activity of phosphoenolpyruvate (...

Ogilvie, Lawrence, 1928: The insects of Bermuda. This preliminary check list is a record of species collected by the author 1923-1928 and of those recorded by previous collectors. Host plants and biological notes are given. In the appendix Aphis ogilviei* (p. 51) is described by F. V. Theobald.

Mccormack, M., 1977: Food service equipment forecast. Activities report: 9 (2) 51-53