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Inhibitors of nitric oxide synthase influence oocyte maturation in rats


, : Inhibitors of nitric oxide synthase influence oocyte maturation in rats. Journal of the Society for Gynecologic Investigation 6(2): 95-101

Female Sprague-Dawley rats (25 days old) were superovulated with a subcutaneous injection of PMSG (10 IU), followed 52 h later by a subcutaneous injection of HCG (10 IU). Three h before and 3 h after HCG injection, the rats were treated orally with vehicle (0.5% methylcellulose; controls) or with 1 of 2 nitric oxide synthase (NOS) inhibitors, N omega -nitro-L-arginine methyl ester (L-NAME) and L-N6-(1-iminoethyl)-lysine (L-NIL).

US$29.90

PMID: 10205780


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