+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of the persistent dominant follicle on the ability of follicle stimulating hormone to induce follicle development and ovulatory responses

, : Effects of the persistent dominant follicle on the ability of follicle stimulating hormone to induce follicle development and ovulatory responses. Journal of Dairy Science 84(1): 88-99

Three experiments were conducted to evaluate the effect of an induced first wave persistent dominant follicle on folliculogenesis and ovulatory responses induced by FSH. On d 6 of a synchronized estrous cycle (d 0 = estrus), cows were treated with a Syncromate-B implant and two injections of PGF(2alpha) (25 mg, 0700 h; 15 mg, 1900 h, i.m.). Cows in the control group retained a first-wave persistent dominant follicle, but in the aspirated group, the first-wave dominant follicle was removed via transvaginal aspiration on d 10 (d 0 = estrus). Beginning on d 12, cows received 32 mg of FSH-P i.m. in decreasing doses at 12-h intervals over a 4-d period. On d 15, the Syncromate-B implant was removed, and cows were ovariectomized (experiment 1, n = 8) or inseminated (experiment 2, n = 11) at 10 and 22 h after the onset of estrus. Cows in experiment 3 received a used controlled intravaginal drug releasing (CIDR) device and two injections of PGF(2alpha) (25 mg, 0700 h; 15 mg, 1900 h; i.m.) on d 6. On d 8, the first-wave dominant follicle was aspirated (n = 6) or left intact (n = 5), and FSH treatment was initiated (20 mg of Folltropin in decreasing doses at 12-h intervals over a 4-d period), and on d 10 the used CIDR device was removed from all cows. Ovarian follicle size and number were examined daily by ultrasonography from d 5 of the estrous cycle. The persistent dominant follicle increased in size from 10.7 mm on d 5 to 15.4 mm on d 10 (experiments 1 and 2), and from 9 mm on d 5 to 20.4 mm on d 11 (experiment 3). From d 11 to 14, the number of class 1 (2 to 5 mm) follicles was lower in the aspirated group than in the control group; the number of class 2 (6 to 9 mm) follicles was higher on d 12 and 13 for the aspirated group (experiments 1 and 2). The number of class 3 (greater than or equal to 10 mm) follicles was higher in the aspirated group on d 14 to 16, but the same on d 17. Ovarian and embryo responses to superovulation did not differ between groups. In experiment 3, the numbers of class 1, 2, and 3 follicles, as well as ovarian and embryo responses following ovulation did not differ between groups. Initiation of exogenous FSH treatment appears to override any systemic inhibitory effect that a persistent dominant follicle may be exerting at the pituitary and possibly the ovary.


PMID: 11210054

DOI: 10.3168/jds.S0022-0302(01)74456-6

Other references

Tang XueDong; L.Y.Dong; L.S.iJu; W.L.n; Zhang ZhiDong, 2005: A comparative study of root activity and mycorrhizal infection incidence of blueberry in different soil conditions. The effects of soil amendments with moss, peat, sawdust, stillage and element S on root activity and mycorrhizal infection incidence of blueberry cv. Northland were studied in pot and field experiments. The root activity and mycorrhizal infection...

Johnson, C.S.; Fales-Williams, A.J.; Reimer, S.B.; Lotsikas, P.J.; Haynes, J.S., 2007: Fibrosing gastrointestinal leiomyositis as a cause of chronic intestinal pseudo-obstruction in an 8-month-old dog. An 8-month-old, female, mixed-breed dog presented to the Iowa State University Veterinary Teaching Hospital with a 1-month history of vomiting and diarrhea. An exploratory laparotomy was performed revealing markedly distended and fluid-filled smal...

Bratcher, L.; Clayton, E.Wright.; Greeley, C., 2007: Children in methamphetamine homes: a survey of physicians practicing in southeast Tennessee. Methamphetamine (meth) abuse in the rural South has increased greatly in the last decade. This addiction harms meth abusers and producers and endangers children who live with them. Appropriate medical evaluation and treatment of these exposed chil...

Bernocchi, P.; Scalvini, S.; Bertacchini, F.; Rivadossi, F.; Muiesan, M.Lorenza., 2014: Home based telemedicine intervention for patients with uncontrolled hypertension--a real life non-randomized study. Control of blood pressure is frequently inadequate in spite of availability of several classes of well tolerated and effective antihypertensive drugs. Several factors, including the use of suboptimal doses of drugs, inadequate or ineffective treat...

Righi, Gilberto, 1964: On the stomach of Thais haemastoma. Details on the anatomy of the stomach are presented. It is located on the left post-torsional side, bounded anteriorly by the digestive gland and posteriorly by the gonad. The body of the organ is well developed with the style sac undeveloped, and...

Rosselle, N.; Clayes, G.; Geens, J.; Geens, H., 1961: Sinaxar in the treatment of muscular contractures. Some clinical observations. Journal Belge de Medecine Physique et de Rhumatologie. Belgisch Tijdschrift Voor Fysische Geneeskunde en Reumatologie 16: 242-248

King, J.S.; Jewett, D.L.; Rutkin, B.; Wilson, C.B., 1977: On attempting selective blockade of dorsal root C fibers in the treatment of chronic pain problems. Experimental Neurology 56(2): 241-251

Anonymous, 1958: CLINICOPATHOLOGIC conference; Ireland Army Hospital, Fort Knox, Ky.; weakness. United States Armed Forces Medical Journal 9(4): 533-542

Sakurai, A., 1992: Phosphorylation of CRE-BP1, a cyclic AMP response element binding protein, by protein kinase C and cyclic AMP-dependent protein kinase. CRE-BP1 is a transcriptional activator binding to the cyclic AMP response element, which has a putative metal finger structure and the leucine zipper motif linked to a cluster of basic amino acids in the amino and carboxyl-terminal regions, respec...

Best, R.; Nelson, S.M.; Walker, B.R., 1997: Metabolism of dexamethasone by the isozymes of 11-beta-hydroxysteroid dehydrogenase. Journal of Endocrinology 152(SUPPL ): P267