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Acute renal failure during severe malaria: pathophysiology and management

, : Acute renal failure during severe malaria: pathophysiology and management. Medecine Tropicale 60(3): 267-270

Renal failure secondary to acute tubular necrosis is a common complication of severe Plasmodium falciparum malaria. Two cases of severe malaria featuring acute renal failure are reported in young French patients who had failed to comply with chemoprophylaxis. Occurrence of renal failure was delayed 4 to 7 days in relation to the beginning of the malaria attack. Haemodialysis was required in one case. Both patients were successfully treated by quinine perfusion.


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