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Effects of caffeine on performance and mood depend on the level of caffeine abstinence


, : Effects of caffeine on performance and mood depend on the level of caffeine abstinence. Psychopharmacology 164(3): 241-249

Rationale: Most studies of the effects of caffeine on performance have used regular caffeine consumers who are deprived at test. Thus the reported effects of caffeine could be explained through reversal of caffeine withdrawal. Objectives: To test how preloading deprived caffeine consumers with 0, 1 or 2 mg/kg caffeine altered the subsequent ability of caffeine to modify mood and performance. Methods: Thirty moderate caffeine consumers were given a drink containing 0, 1 or 2 mg/kg caffeine at breakfast followed 60 min later by a second drink containing either 0 or 1 mg/kg caffeine. Performance on a measure of sustained attention and mood were measured before and after each drink. Results: Administration of both 1 and 2 mg/kg caffeine at breakfast decreased reaction time and 1 mg/kg caffeine also increased performance accuracy on the sustained attention (RVIP) task relative to placebo. Both breakfast doses of caffeine also improved rated mental alertness. Similarly, 1 mg/kg caffeine administered 60 min after breakfast decreased reaction time and increased rated mental alertness in the group who had not been given caffeine at breakfast. However, this second dose of caffeine had no effect on subsequent performance or mood in the two groups who had received caffeine at breakfast. Conclusions: Caffeine reliably improved performance on a sustained attention task, and increased rated mental alertness, in moderate caffeine consumers who were tested when caffeine-deprived. However, caffeine had no such effects when consumers were no longer caffeine deprived. These data are consistent with the view that reversal of caffeine withdrawal is a major component of the effects of caffeine on mood and performance.

US$19.90

PMID: 12424547

DOI: 10.1007/s00213-002-1204-1


Other references

Rako, A., 1976: The problems and results of breeding cattle by crossbreeding in western Europe. Stocarstvo 30 (9 10) 269-282

Kureshy A.A., 1972: Sedimentary basins of West Pakistan. Pakistan Journal of Scientific Research 24(1-2): 132-138

Sarnat, B.G., 2003: Gross growth and regrowth of sutures: reflections on some personal research. A series of experiments was performed on young monkeys, rabbits, and turtles to study gross sutural growth of bones. Radiopaque implants in conjunction with serial, direct gross, and indirect radiographic measurements were employed. Differences in...

Treharne, L.J.; Banwell, P.; Cadier, M., 2003: Mandatory bone scans for the assessment of extremity loss in meningococcal septicaemia?. Meningococcal septicaemia can cause progressive necrosis of skin, soft tissue and bone. Successful limb reconstruction following the disease depends on an accurate assessment of the viability of these tissues and on a multidisciplinary team approa...

Lou, B-Show.; Wu, P-Shan.; Hou, C-Wei.; Cheng, F-Yin.; Chen, J-Kan., 2014: Simultaneous quantification of trans-resveratrol and its sulfate and glucuronide metabolites in rat tissues by stable isotope-dilution UPLC-MS/MS analysis. A rapid, sensitive, and selective ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) in the multiple reaction monitoring (MRM) mode has been developed and validated to investigate the distribution of trans-Resveratrol (R...

McKenzie, D., 1924: Removal of Thyro-Glossal Duct and Fistula; Ten Years after Operation. Proceedings of the Royal Society of Medicine 17(Laryngol Sect): 85-86

Kamensky, W.K., 1931: On the distribution of coccidiosis in the Turkmen Republic. Trop Med Vet Moscow, 9: 276-278

Liu, H-Cheng.; Tao, W-Ke.; Zeng, R-Feng.; ShangGuang, W-Ning.; Li, J.; Huang, W-Guang.; Dong, Z-Lei.; Wang, X.; Lian, Q-Quan., 2014: Dose requirements of remifentanil for intubation in nonparalyzed Chinese children. The objective of this study was to determine ED50 and ED95 of remifentanil for intubation combined with propofol in nonparalyzed Chinese children. Forty-seven American Society of Anesthesiologists Class I children aged 4-11 years weighing 14-33.5...

Merino, J.; García-Conde, J.; Benet, I., 1977: A functional assay of fibrinoformation in the newborn. Sangre 22(4): 439-452

Tseng, S.H.; Hwang, L.H.; Lin, S.M., 1997: Induction of antitumor immunity by intracerebrally implanted rat C6 glioma cells genetically engineered to secrete cytokines. To test whether cytokine gene therapy can be applied to an immunologically privileged site, such as the brain, we investigated antitumor immunity in the brain induced by cytokine-secreting glioma cells. Three cytokine genes, interleukin-2 (IL-2),...