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Identification and characterization of major allergens in excretory/secretory products of the worm Paragonimus ohirai

, : Identification and characterization of major allergens in excretory/secretory products of the worm Paragonimus ohirai. International Archives of Allergy and Immunology 128(3): 187-194

Allergens present in the excretory/secretory (ES) products of adult Paragonimus ohirai were biochemically identified. Immunoblot analysis using sera from P. ohirai-infected rats revealed only two allergens to be major proteins in the ES products, with apparent molecular masses (M<sub>r</sub>) of 27 and 29 kD. As the ES products contained a high proportion of acidic and neutral cysteine proteinases, we examined whether or not the allergens and the cysteine proteinases were identical.


PMID: 12119500

DOI: 10.1159/000064251

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