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Identification and cloning of a cryptococcal deacetylase that produces protective immune responses

, : Identification and cloning of a cryptococcal deacetylase that produces protective immune responses. Infection and Immunity 70(5): 2383-2391

Cell-mediated immunity plays a crucial role in host defenses against Cryptococcus (Filobasidiella) neoformans. Therefore, the identification of cryptococcal antigens capable of producing T-cell-mediated responses, such as delayed-type hypersensitivity (DTH) reactions, may be useful in the development of immune-based strategies to control cryptococcosis.


PMID: 11953374

DOI: 10.1128/IAI.70.5.2383-2391.2002

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